Hyperprolactinaemia means that the level of a hormone called prolactin in your blood is higher than the normal range for your age and sex. Prolactin is made by the pituitary gland, a small organ at the base of the brain. Read More …
Acromegaly
Acromegaly is a long-term (chronic) hormone disorder in adults. It happens when the pituitary gland, a small gland at the base of the brain, makes too much growth hormone (GH) for a long time. The high GH makes the liver Read More …
Hypothalamic Hamartoma
A hypothalamic hamartoma is a small, non-cancer growth made of normal brain cells that are in the wrong place in the hypothalamus, a deep part of the brain that controls hormones, sleep, temperature, hunger, and many body rhythms. It forms Read More …
Neurogenic Diabetes Insipidus
Neurogenic diabetes insipidus is a brain-related water-balance disorder. In this condition, the brain does not make or release enough of a hormone called antidiuretic hormone (ADH), also known as arginine vasopressin (AVP). ADH normally helps the kidneys save water and Read More …
Tertiary Adrenal Insufficiency
Tertiary adrenal insufficiency is a condition where the brain, especially the hypothalamus, does not send enough signals to tell the adrenal glands to make cortisol, an important stress hormone. In this condition, the adrenal glands themselves are usually normal, but Read More …
Adiposogenital Dystrophy
Adiposogenital dystrophy is a rare hormone disorder where a problem in the brain (mainly the hypothalamus and pituitary region) causes obesity plus low sex hormone levels (hypogonadism). Children or teenagers with this condition usually gain a lot of weight, grow Read More …
Kallmann Syndrome
Kallmann syndrome is a rare genetic condition where the brain does not make enough gonadotropin-releasing hormone (GnRH). Because of this, the body makes very low levels of the sex hormones (testosterone in males, oestrogen and progesterone in females). Puberty is Read More …
Insulitis
Insulitis means inflammation inside the tiny insulin-making parts of the pancreas, called the islets of Langerhans. In this condition, many immune cells (T cells, B cells, macrophages and other white blood cells) move into and around the islets. They crowd Read More …
Insulinoma
Insulinoma is a rare tumor that grows from the insulin-making beta cells in the pancreas. These tumor cells release insulin all the time, even when blood sugar is already low. This extra insulin pushes blood sugar down and causes repeated Read More …
Pancreatic Beta Cell Dysfunction
Pancreatic beta cell dysfunction means that the special cells in the pancreas that make insulin are not working properly. These beta cells live in small groups called islets, and their main job is to sense the level of sugar (glucose) Read More …
Rabson–Mendenhall Syndrome (RMS)
Rabson–Mendenhall syndrome (RMS) is a very rare genetic disease in which the body’s cells do not respond properly to insulin. This problem is called severe insulin resistance. Insulin is a hormone made by the pancreas that helps sugar (glucose) move Read More …
Congenital Hyperinsulinism
Congenital hyperinsulinism is a disease in which a baby or child makes too much insulin from the pancreas, even when the blood sugar is already low. Insulin is a hormone that normally helps move sugar (glucose) from the blood into Read More …